Medical Professional

Component /Product	Composition	Volume	Indications	Acute complicatios	Delayed complication
Whole blood	RBC [ Approx. Hct 40% plasma ; WBC and platelets	About 450 ml	Increase both red cell mass and plasma volume [WBC & Platelets are not functional ; plasma deficient in labile clotting factors V,VIII]	Hemolytic febrile , allergic and anaphylaxis	delayed hemolytic reaction - post transfusion purpura - transfusion transmitted infection
Red Blood cells	RBC [ Approx. Hct 75%] reduced plasma ; WBC and platelets	250 ml	Increase red cell mass in symptomatic anemia [ WBC and platelets not functional]	Hemolytic febrile , allergic and anaphylaxis	delayed hemolytic reaction - post transfusion purpura - transfusion transmitted infection
Red Blood cells , Additive soultion	RBC [ Approx. Hct 60%] reduced plasma ; WBC and platelets , 100 ml of additive solutions	330 ml	Increase red cell mass in symptomatic anemia [ WBC and platelets not functional]	Hemolytic febrile , allergic and anaphylaxis	delayed hemolytic reaction - post transfusion purpura - transfusion transmitted infection
Leukocyte Reduced RBC [prepared by filtration or centrifugation]	RBC [Approx. HCT 75%]; few platelets; minimal plasma; <5X10⁶ to <5X10⁸ WBC	About 220 ml	Increase red cell mass ; prevent febrile reaction due to Leukocyte antibodies ; decrease the possibility of immunization to Leukocyte or HLA antigens	Hemolytic febrile , allergic and anaphylaxis	delayed hemolytic reaction - post transfusion purpura - transfusion transmitted infection
Washed RBC	RBC [ Approx. Hct 75%] <5X10⁸ WBC ; no platelets ; no plasma	About 220 ml	Increase red cell mass ; reduce risk of allergic reactions to plasma proteins	Hemolytic and febrile	delayed hemolytic reaction - post transfusion purpura - transfusion transmitted infection
RBC frozen /deglycerolized	RBC [ Approx. Hct 75%] <5X10⁸ WBC ; no platelets ; no plasma	180 ml	Increase red cell mass ; reduce risk of febrile or allergic reaction used	Hemolytic	delayed hemolytic reaction - post transfusion purpura - transfusion transmitted infection
Platelets (random donor)	Platelets [ >0.5X10¹¹ /unit];RBC; plasma	50 ml	Bleeding due to thrombasthenia or thrombocy topenia	Febrile ,allergic and anaphylaxis	delayed hemolytic reaction - post transfusion purpura - transfusion transmitted infection
Platelets a pheresis	Platelets [>3X10¹¹/unit] RBC; plasma	About 250 ml	Same as Platelets ; sometimes HLA matched	Same as Platelets	delayed hemolytic reaction - post transfusion purpura - transfusion transmitted infection
Granulocytes a pheresis	Granulocytes , lymphocytes ; platelets [ <1X10¹⁰ PMN/unit ; > 2X10¹⁰ platelets/unit] RBC	220 ml	provide Granulocytes for selected patients	Hemolytic febrile and allergic	delayed hemolytic reaction - post transfusion purpura - transfusion transmitted infection
Fresh frozen plasma FFP	Plasma ; all coagulation factors ; complement (no platelets)	About 180 ml	Treatment of some coagulation disorders	Allergic and anaphylaxis, rarely hemolytic	delayed hemolytic reaction - post transfusion purpura - transfusion transmitted infection
Cryoprecipitated AHF	Fibrinogen ; F VIII ; F XIII ; vWF and fibronectin	About 40 ml	Hemophilia A ; vW disease ; Fibrinogen deficiency and F XIII deficiency	Allergic and anaphylaxis	delayed hemolytic reaction - post transfusion purpura - transfusion transmitted infection